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Record W2145905923 · doi:10.1503/cmaj.091692

Anatomic distribution of deep vein thrombosis in pregnancy

2010· review· en· W2145905923 on OpenAlexafffundvenue
Wai‐Sum Chan, Frederick A. Spencer, J. S. Ginsbergm

Bibliographic record

VenueCanadian Medical Association Journal · 2010
Typereview
Languageen
FieldMedicine
TopicVenous Thromboembolism Diagnosis and Management
Canadian institutionsUniversity of Toronto
FundersHeart and Stroke Foundation of Canada
KeywordsMedicineDeep veinThrombosisPregnancyFemoral veinVeinCochrane LibrarySurgeryRadiologyVenous thrombosisRandomized controlled trial

Abstract

fetched live from OpenAlex

BACKGROUND: Prospective studies of nonpregnant patients have demonstrated that most deep vein thromboses of the lower extremity originate in the calf veins and progress proximally, but the anatomic distribution of thromboses in pregnant patients is unclear. An understanding of the anatomic distribution of deep vein thrombosis in pregnancy has important implications for optimizing diagnostic imaging protocols. We undertook this study to determine the anatomic distribution of deep vein thrombosis of the lower extremity in symptomatic pregnant patients. METHODS: We systematically searched MEDLINE (1966 to January 2009), Embase (1980 to January 2009) and the Cochrane Library using prespecified criteria to identify articles providing objective diagnostic and anatomic information for unselected or consecutive symptomatic pregnant patients with deep vein thrombosis. RESULTS: Six articles from an initial list of 1098 titles met the inclusion criteria. These articles provided information for 124 pregnant women with a diagnosis of deep vein thrombosis. Overall, involvement of the left leg was reported in 84 (88%) of the 96 patients for which the side affected was known, and 87 (71%) of 122 thromboses were restricted to the proximal veins without involvement of the calf veins. Among these cases of proximal deep vein thrombosis, 64% (56/87) were restricted to the iliac and/or femoral vein. CONCLUSION: Despite a paucity of studies in this area, the results of our review suggest that the anatomic distribution of deep vein thrombosis in pregnant women differs from that for nonpregnant patients. In addition to what was previously known--that left-sided deep vein thrombosis is more common in pregnancy--we also found that proximal deep vein thrombosis restricted to the femoral or iliac veins is also more common (> 60% of cases). If confirmed by larger studies, these findings could affect our understanding of the pathophysiology and derivation of diagnostic algorithms for examination of pregnant women with suspected deep vein thrombosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.982
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.304
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations166
Published2010
Admission routes3
Has abstractyes

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