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Record W2147024435 · doi:10.1086/376549

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia

2003· article· en· W2147024435 on OpenAlexaff
Cathryn M. Lewis, Douglas F. Levinson, Lesley H. Wise, Lynn E. DeLisi, Richard E. Straub, Iiris Hovatta, Nigel Williams, Sibylle G. Schwab, Ann E. Pulver, Stephen V. Faraone, Linda M. Brzustowicz, Charles A. Kaufmann, David L. Garver, Hugh Gurling, Eva Lindholm, Hilary Coon, Hans W. Moises, William Byerley, Sarah H. Shaw, Andrea Mesén, Robin Sherrington, F. Anthony O’Neill, Dermot Walsh, Kenneth S. Kendler, Jesper Ekelund, Tiina Paunio, Jouko Lönnqvist, Leena Peltonen, Michael O‘Donovan, Michael J. Owen, Dieter B. Wildenauer, Wolfgang Maier, Gerald Nestadt, Jean‐Louis Blouin, Stylianos E. Antonarakis, Bryan Mowry, Jeremy M. Silverman, Raymond R. Crowe, C. Robert Cloninger, Ming T. Tsuang, Dolores Malaspina, Jill Harkavy‐Friedman, Dragan M. Švrakić, Anne S. Bassett, Jennifer Holcomb, Gursharan Kalsi, Andrew McQuillin, Jon Brynjolfson, Thordur Sigmundsson, Hannes Pétursson, Elena Jazin, Tómas Zoëga, Tómas Helgason

Bibliographic record

VenueThe American Journal of Human Genetics · 2003
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Associations and Epidemiology
Canadian institutionsUniversity of TorontoXenon Pharmaceuticals (Canada)
FundersNational Institute of Mental HealthWellcome Trust
KeywordsSchizophrenia (object-oriented programming)Bipolar disorderMeta-analysisPsychiatryPsychologyGenome ScanMedicineGeneticsBiologyCognitionGeneInternal medicineAllele

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.018
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (broad)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.995
Threshold uncertainty score0.064

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.018
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0050.019
Bibliometrics0.0040.005
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0020.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.279
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1,146
Published2003
Admission routes1
Has abstractno

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