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Record W2147960554 · doi:10.1109/csb.2004.1332487

Exploring the use of stem-loop characteristics for pinpointing structural RNA genes

2004· article· en· W2147960554 on OpenAlexaff
Kirt M. Noël, Kay C. Wiese

Bibliographic record

VenueProceedings. 2004 IEEE Computational Systems Bioinformatics Conference, 2004. CSB 2004. · 2004
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRNA and protein synthesis mechanisms
Canadian institutionsSimon Fraser University
Fundersnot available
KeywordsLoop (graph theory)Computational biologyMetric (unit)Stem-loopGeneRNABiologyStem cellComputer scienceGeneticsMathematicsEngineeringCombinatorics

Abstract

fetched live from OpenAlex

Our goal is to determine whether a stem-loop metric or combination of stem-loop metrics can be used to identify structural RNAs along genomic sequences across the entire GC content spectrum. Herein we describe the first step towards this goal by comparing selected stem-loop metric valuations between structural RNAs and their genomic counterparts.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0030.002
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.097
GPT teacher head0.254
Teacher spread0.157 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2004
Admission routes1
Has abstractyes

Explore more

Same venueProceedings. 2004 IEEE Computational Systems Bioinformatics Conference, 2004. CSB 2004.Same topicRNA and protein synthesis mechanismsFrench-language works237,207