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Record W2149114501 · doi:10.1111/dme.13023

The association between sociodemographic and clinical characteristics and poor glycaemic control: a longitudinal cohort study

2015· article· en· W2149114501 on OpenAlexafffund
Kerry McBrien, Braden Manns, Brenda R. Hemmelgarn, Robert G. Weaver, Alun Edwards, Noah Ivers, Doreen M. Rabi, R. Lewanczuk, Tali Braun, Christopher Naugler, David J.T. Campbell, Nathalie Saad, Marcello Tonelli

Bibliographic record

VenueDiabetic Medicine · 2015
Typearticle
Languageen
FieldMedicine
TopicDiabetes, Cardiovascular Risks, and Lipoproteins
Canadian institutionsUniversity of AlbertaUniversity of TorontoWomen's College HospitalAlberta Health ServicesLibin Cardiovascular Institute of AlbertaCalgary Laboratory ServicesAlberta HealthUniversity of Calgary
FundersAlberta Innovates - Health SolutionsGovernment of AlbertaAlberta Health Services
KeywordsMedicineCohortAssociation (psychology)Cohort studyGerontologyInternal medicineDemography

Abstract

fetched live from OpenAlex

Abstract Aims People with diabetes and poor glycaemic control are at higher risk of diabetes‐related complications and incur higher healthcare costs. An understanding of the sociodemographic and clinical characteristics associated with poor glycaemic control is needed to overcome the barriers to achieving care goals in this population. Methods We used linked administrative and laboratory data to create a provincial cohort of adults with prevalent diabetes, and a measure of HbA 1c that occurred at least 1 year following the date of diagnosis. The primary outcome was poor glycaemic control, defined as at least two consecutive HbA 1c measurements ≥ 86 mmol/mol (10%), not including the index measurement, spanning a minimum of 90 days. We used multivariable Cox proportional hazards models to evaluate the association between baseline sociodemographic and clinical factors and poor glycaemic control. Results In this population‐based cohort of 169 890 people, younger age was significantly associated with sustained poor glycaemic control, with a hazard ratio ( HR ) of 3.08, 95% CI (2.79–3.39) for age 18–39 years compared with age ≥ 75 years. Longer duration of diabetes, First Nations status, lower neighbourhood income quintile, history of substance abuse, mood disorder, cardiovascular disease, albuminuria and high LDL cholesterol were also associated with poor glycaemic control. Conclusions Although our results may be limited by the observational nature of the study, the large geographically defined sample size, longitudinal design and robust definition of poor glycaemic control are important strengths. These findings demonstrate the complexity associated with poor glycaemic control and indicate a need for tailored interventions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.058
Threshold uncertainty score0.650

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0080.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.306
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations30
Published2015
Admission routes2
Has abstractyes

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