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Record W2149378423 · doi:10.1186/2041-1480-1-s1-s7

Modeling biomedical experimental processes with OBI

2010· article· en· W2149378423 on OpenAlexafffund
Ryan R. Brinkman, Mélanie Courtot, Dirk Derom, Jennifer Fostel, Yongqun He, Phillip Lord, James Malone, Helen Parkinson, Bjoern Peters, Philippe Rocca‐Serra, Alan Ruttenberg, Susanna‐Assunta Sansone, Larisa Soldatova, Christian J. Stoeckert, Jessica A. Turner, Jie Zheng

Bibliographic record

VenueJournal of Biomedical Semantics · 2010
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBiomedical Text Mining and Ontologies
Canadian institutionsBC Cancer Agency
FundersNational Center for Research ResourcesNational Institute of Environmental Health SciencesEngineering and Physical Sciences Research CouncilNatural Environment Research CouncilBiotechnology and Biological Sciences Research CouncilCanadian Institutes of Health ResearchNational Institute of Mental HealthPublic Health AgencyPublic Health Agency of CanadaNational Institutes of HealthNational Institute of Biomedical Imaging and BioengineeringMichael Smith Health Research BCNational Institute of Allergy and Infectious DiseasesNERC Environmental Bioinformatics Centre
KeywordsComputer scienceData scienceTerminologyOntologyProcess (computing)Semantic WebInterpretation (philosophy)Information retrievalEpistemologyProgramming language

Abstract

fetched live from OpenAlex

BACKGROUND: Experimental descriptions are typically stored as free text without using standardized terminology, creating challenges in comparison, reproduction and analysis. These difficulties impose limitations on data exchange and information retrieval. RESULTS: The Ontology for Biomedical Investigations (OBI), developed as a global, cross-community effort, provides a resource that represents biomedical investigations in an explicit and integrative framework. Here we detail three real-world applications of OBI, provide detailed modeling information and explain how to use OBI. CONCLUSION: We demonstrate how OBI can be applied to different biomedical investigations to both facilitate interpretation of the experimental process and increase the computational processing and integration within the Semantic Web. The logical definitions of the entities involved allow computers to unambiguously understand and integrate different biological experimental processes and their relevant components. AVAILABILITY: OBI is available at http://purl.obolibrary.org/obo/obi/2009-11-02/obi.owl.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.015
Threshold uncertainty score0.038

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.014
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.004
Bibliometrics0.0050.005
Science and technology studies0.0010.002
Scholarly communication0.0060.006
Open science0.0030.004
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.277
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations286
Published2010
Admission routes2
Has abstractyes

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