Inhibition of Successive Positive Contrast in Rats Withdrawn from an Escalating Dose Schedule of D-amphetamine
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Rats in a vehicle treated control condition when shifted from 4% to 32% sucrose displayed successive positive contrast by responding at a significantly higher lick rate in a 5 min trial than rats maintained on 32% sucrose throughout the experiment. In contrast, rats treated with an escalating dose regimen of D-amphetamine (1-10 mg/kg) over a 4 day interval failed to display successive positive contrast. Withdrawal from drug treatment had no effect on lick rate or response latency in rats maintained on 32% sucrose. These data are consistent with many previous reports that withdrawal from a binge-like regimen of psychostimulant drug administration disrupts responding for natural reward stimuli. These findings support the use of psychostimulant withdrawal as a model of drug-induced dysphoria and suggest that incentive contrast is a particularly sensitive measure of these changes in motivation and emotion.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it