Unlocking the secrets of the genome
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.
Abstract
Despite the successes of genomics, little is known about how genetic information produces complex organisms. A look at the crucial functional elements of fly and worm genomes could change that. The National Human Genome Research Institute's modENCODE project (the model organism ENCyclopedia Of DNA Elements) was set up in 2007 with the goal of identifying all the sequence-based functional elements in the genomes of two important experimental organisms, Caenorhabditis elegans and Drosophila melanogaster. Armed with modENCODE data, geneticists will be able to undertake the comprehensive molecular studies of regulatory networks that hold the key to how complex multicellular organisms arise from the list of instructions coded in the genome. In this issue, modENCODE team members outline their plan of campaign. Data from the project are to be made available on http://www.modencode.org and elsewhere as the work progresses.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Nature
- Topic
- Genetics, Aging, and Longevity in Model Organisms
- Field
- Biochemistry, Genetics and Molecular Biology
- Canadian institutions
- —
- Funders
- Lawrence Berkeley National LaboratoryNational Institute of General Medical SciencesNational Human Genome Research InstituteComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of TechnologyYork UniversityArgonne National LaboratoryUniversity of North Carolina at Chapel HillBroad InstituteMassachusetts Institute of TechnologyUniversity of WashingtonHarvard UniversityNational Institutes of HealthYale University
- Keywords
- Caenorhabditis elegansGenomeMulticellular organismOrganismModel organismBiologyGenomicsDrosophila melanogasterEncyclopediaComputational biologyKey (lock)Plan (archaeology)Data scienceEvolutionary biologyGeneticsComputer scienceEcologyGeneLibrary science
- Has abstract in OpenAlex
- yes