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Record W2151818970 · doi:10.1111/cns.12478

The 1st Annual Conference of <scp>CSA</scp> and <scp>TISC</scp> 2015

2015· article· en· W2151818970 on OpenAlexaboutno aff
Liping Liu

Bibliographic record

VenueCNS Neuroscience & Therapeutics · 2015
Typearticle
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineStroke (engine)GuidelineChinaRandomized controlled trialClinical trialPopulationSubgroup analysisFamily medicineMeta-analysisInternal medicinePathologyPolitical scienceEnvironmental health

Abstract

fetched live from OpenAlex

The 1st Annual Conference of Chinese Stroke Association (CSA) and Tiantan International Stroke Conference (TISC 2015) was held at the China National Conference Center (CNCC) in Beijing from June 26–28, 2015. Many domestic and international scholars and experts who are focusing on cerebrovascular disease discussed the development of CSA, the international cooperation, development strategies, and other issues together. Tens of thousands of people participated in the distinguished gathering and dozens of sessions were involved in the major conference in the field of cerebrovascular disease. In China, stroke has become the first cause of death and disability. The level of prevention and treatment of stroke needs to be improved and has made a breakthrough in 2014—endovascular treatment. In 2015, New England Journal of Medicine published five clinical randomized studies on endovascular thrombectomy from Holland, Canada, the USA, Europe, Australia, and Spain. The results showed that the recanalization rate and brain tissue reperfusion degree could be significantly improved and neurological outcomes would be better for patients with acute ischemic stroke who met the inclusion criteria after being taken the endovascular thrombectomy. Due to the significant medium-term efficacy of test group, four studies were terminated ahead of time. Consensus of experts in Europe and the USA pointed out that the evidence-based medicine listed as grade IA owing to the definite efficacy of this therapy, the significant benefit which outweighed the risks, numerous study population, and data which sources from multiple randomized trials or meta analysis. In the same year, Chinese experts updated the guideline kept ahead of Europe and the USA and formulated “Chinese guideline for the diagnosis and treatment of acute ischemic stroke 2015”. This treatment of acute stroke is a major technological change in the improvement of the effect and the prognosis of patients. However, at present, there are still less than 50 hospitals which can carry out the endovascular thrombectomy and the number of cases is less than 1800 every year. Therefore, it is in urgent need of the extensive technical training in China and steadily standardizes the promotion of this new technology, in order to make more patients in acute ischemic stroke benefit. Dr. Marc Fisher, Chief Editor of journal STROKE, presented at plenary session on Sat. morning. For the prevention and control of stroke, “Time is brain”! Medical media organizations should publicize emergency knowledge of stroke to the majority of patients and their families, and achieve “two early”: one is that patients with the related symptoms of stroke should arrive the hospital with the qualification of thrombolysis and thrombectomy as soon as possible instead of wait; another is to help patients understand that which technologies can help patients reduce mortality and improve the prognosis, and to clear the good curative effect of thrombolysis and endovascular thrombectomy for ischemic stroke and the benefits which far outweigh the risks. Let patients cooperate with the hospital and make a decision as soon as possible so as to gain valuable time to diagnosis and treatment. Professor Stephen Davis, President of WSO, had a view on the diagnosis and treatment of stroke then. He believes that there is a huge revolutionary change in the treatment of stroke, which is caused by a blockage of blood flow. Global patients at least about 10% every year (ie, about 200–300 million) are suitable for the endovascular thrombectomy. The important task is to let patients and their families understand the technology and arrive the hospital with the qualification in time to receive the treatment. Professor Davis indicated that endovascular thrombectomy is a great progress and he firmly believed that this technology would get good quality control and check and China must lead the trend of world in thrombectomy. But still, many issues need to be addressed. The main three big changes in the current international clinical research are as follows: (1) patients with large vessel obstruction were selected, (2) to emphasize the method of mechanical thrombectomy, most patients take the new generation stent device of thrombectomy, and (3) most studies emphasized that the patients should have ischemic penumbra and incomplete necrotic brain tissue. Past researches have shown that although patients achieved the revascularization, the clinical prognosis was not good. Now these studies suggest that a reasonable selection of patients and thrombectomy for the valuable patient can lead to high recanalization rate and the improvement in probability of self-care among 3 months. The latest research results showed that one patient might obtain the ability to live independently among 3–4 patients, so as to create a good foundation for future treatment!

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.524
Threshold uncertainty score0.817

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.304
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2015
Admission routes1
Has abstractyes

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