Pathophysiology of ovarian hyperstimulation syndrome and strategies for its prevention and treatment
Bibliographic record
Abstract
Ovarian hyperstimulation syndrome (OHSS) is characterized by ovarian enlargement, ascites and pleural effusion. Most cases of OHSS develop after ovarian stimulation with gonadotropins. The basis of the process is increased vascular permeability, and this is related to VEGF. VEGF is produced in granulosa cells in response to gonadotropin stimulation and its secretion is augmented following human chorionic gonadotropin administration. One of the major risk factors is polycystic ovaries. Preventive strategies include mild stimulation protocols, coasting, in vitro maturation, infusion of macromolecule solutions and coadministration of dopamine agonists. OHSS is a self-limiting condition and most cases can be managed with paracentesis and fluid replacement. In this article, we review pathogenesis, risk factors, strategies for prevention and management of OHSS.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".