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Record W2155840407

Lipidomic and Genomic Investigation of Mahoney Lake, B.C.

2014· dissertation· en· W2155840407 on OpenAlexaboutno aff
Roderick Bovee

Bibliographic record

VenueDigital Access to Scholarship at Harvard (DASH) (Harvard University) · 2014
Typedissertation
Languageen
FieldEnvironmental Science
TopicFish Ecology and Management Studies
Canadian institutionsnot available
Fundersnot available
KeywordsComputational biologyBiologyData scienceGeneticsComputer science
DOInot available

Abstract

fetched live from OpenAlex

Photic-zone euxinia (PZE) is associated with several times in Earth's history including Phanerozoic extinction events and long parts of the Proterozoic. One of the best modern analogues for extreme PZE is Mahoney Lake in British Columbia, Canada where a dense layer of purple sulfur bacteria separate the oxic mixolimnion from one of the most sulfidic monimolimnions in the world. These purple sulfur bacteria are known to produce the carotenoid okenone. Okenone's diagenetic product, okenane, has potential as a biomarker for photic-zone euxinia, so understanding its production and transport is important for interpreting the geologic record. In the following dissertation, I examine Mahoney Lake with a multi-proxy approach. I use lipid biomarkers to understand organic matter production burial in the lake and find strong evidence of lateral transport of organic matter from shoreline microbial mats to the lake-bottom sediments. I also find evidence of okenone production in these shoreline mats and a carotenoid previously unreported in the environment, Thiothece-484, associated with the okenone synthetic pathway. Finally, I develop a new bioinformatics method to examine high-throughput metagenomic data and use this method to start understanding how the metabolic and lipid synthetic pathways of microbial communities in the lake are associated with each other.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.972
Threshold uncertainty score0.055

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.211
Teacher spread0.198 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2014
Admission routes1
Has abstractyes

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