Phytochemical and Antitrypanosomal Studies of Different Solvents Extracts of Boswellia dalzielii
Bibliographic record
Abstract
Solvent extracts of the various parts of Boswellia dalzielii (leaves, stem bark and root bark) were screened invitro and in vivo for antitrypanosomal activity against Trypanosoma brucei brucei. Methanolic extract of theleaves, stem bark and root bark of Boswellia dalzielii at 20 mg/ml caused motility to cease after 35, 20 and 20minutes, respectively while at 10 mg/ml, motility ceased at 50, 30 and 20 minutes respectively. Chloroformextract of root bark of the plant caused motility to cease after 40 minutes at concentration of 20 mg/ml. In vivoactivity of methanol extract of the plant on T. brucei brucei infected mice showed consistent parasitemicsuppressions at 300 mg/kg with methanolic extract of the leaves displaying highest activity. Reagent-basedchemical analysis conducted on the extract revealed the presence of saponins, alkaloids, flavonoids, tannins,resins, steroids and triterpenes. These findings suggest that methanolic extract of Boswellia dalzielii leaves ismore effective than other parts of the plant, and hence deserve further evaluation in the therapy oftrypanosomiasis.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".