Internalizing the vegetal cell mass before and during amphibian gastrulation: vegetal rotation and related movements
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The movement of the prospective mesoderm and endoderm to the interior of the amphibian embryo starts in the vegetal cell mass well before the onset of overt gastrulation. By an animally directed movement of cells, the vegetal mass constricts its outer part and expands its inner region including the blastocoel floor, in a process of pregastrulation emboly. Further internalization of the vegetal region has been studied in the Xenopus embryo. At the onset of gastrulation, vegetal rotation sets in at the periphery of the vegetal cell mass, first dorsally and then spreading laterally and ventrally. It consists of an intense inward surging of cells due to active cell rearrangements that can be observed in explants of the vegetal cell mass. In its course, the blastocoel floor expands further and becomes apposed to the blastocoel roof. The boundary between apposed floor and roof forms Brachet's cleft. Another effect of vegetal rotation is the downward and inward movement of the mesodermal marginal zone, constituting the first phase of involution. Together, the upward and outward movement of the peripheral vegetal mass and the downward and inward translocation of the marginal zone lead to an apparent rotation of the whole peripheral region of the gastrula. Vegetal rotation continues to contribute to endoderm internalization to near the end of gastrulation.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.003 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it