On testing the bioequivalence of several treatments using the measure of distance
Why this work is in the frame
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Bibliographic record
Abstract
A studentized range test is proposed to test the hypothesis of bioequivalence of normal means in terms of a standardized distance among means. A least favourable configuration (LFC) of means to guarantee the maximum level at a null hypothesis and an LFC of means to guarantee the minimum power at an alternative hypothesis are obtained. This level and power of the test are fully independent of the unknown means and variances. For a given level, the critical value of the test under a null hypothesis can be determined. Furthermore, if the power under an alternative is also required at a given level, then both the critical value and the required sample size for an experiment can be simultaneously determined. In situations where the common population variance is unknown and the bioequivalence is the actual distance between means without standardization, a two-stage sampling procedure can be employed to find these solutions.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.101 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it