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Record W2160506991 · doi:10.1126/science.1195203

Signatures of Adaptation to Obligate Biotrophy in the <i>Hyaloperonospora arabidopsidis</i> Genome

2010· article· en· W2160506991 on OpenAlexaff
Laura Baxter, Sucheta Tripathy, Naveed Ishaque, Nico Boot, Adriana Cabral, Eric Kemen, Marco Thines, Audrey M. V. Ah‐Fong, Ryan G. Anderson, Wole Badejoko, Peter D. Bittner‐Eddy, Jeffrey L. Boore, Marcus C. Chibucos, Mary Coates, Paramvir Dehal, Kim D. Delehaunty, Suomeng Dong, Polly Downton, Bernard Dumas, Georgina Fabro, Catrina C. Fronick, Susan I. Fuerstenberg, Lucinda Fulton, Elodie Gaulin, Francine Govers, Linda Karen Hughes, Sean Humphray, Rays H. Y. Jiang, Howard S. Judelson, Sophien Kamoun, Kyung Kim, H.J.G. Meijer, Patrick Minx, Paul F. Morris, Joanne O. Nelson, Vipaporn Phuntumart, Dinah Qutob, Anne P. Rehmany, Alejandra Rougon‐Cardoso, Peter Ryden, Trudy Torto-Alalibo, David J. Studholme, Yuanchao Wang, Joe Win, Jonathan Wood, Sandra W. Clifton, Jane Rogers, Guido Van den Ackerveken, Jonathan D. G. Jones, John M. McDowell, Jim Beynon, Brett M. Tyler

Bibliographic record

VenueScience · 2010
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPlant Pathogens and Resistance
Canadian institutionsAgriculture and Agri-Food Canada
FundersBiotechnology and Biological Sciences Research CouncilWellcome Trust
KeywordsObligateOomyceteBiologyGenomeBotanyGeneticsGene

Abstract

fetched live from OpenAlex

From Blight to Powdery Mildew Pathogenic effects of microbes on plants have widespread consequences. Witness, for example, the cultural upheavals driven by potato blight in the 1800s. A variety of microbial pathogens continue to afflict crop plants today, driving both loss of yield and incurring the increased costs of control mechanisms. Now, four reports analyze microbial genomes in order to understand better how plant pathogens function (see the Perspective by Dodds ). Raffaele et al. (p. 1540 ) describe how the genome of the potato blight pathogen accommodates transfer to different hosts. Spanu et al. (p. 1543 ) analyze what it takes to be an obligate biotroph in barley powdery mildew, and Baxter et al. (p. 1549 ) ask a similar question for a natural pathogen of Arabidopsis . Schirawski et al. (p. 1546 ) compared genomes of maize pathogens to identify virulence determinants. Better knowledge of what in a genome makes a pathogen efficient and deadly is likely to be useful for improving agricultural crop management and breeding.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.204
Teacher spread0.192 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations462
Published2010
Admission routes1
Has abstractyes

Explore more

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