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Record W216206898

JP-8 Jet Fuel: Genotoxic and Cytotoxic Studies in Experimental Animals

2007· article· en· W216206898 on OpenAlexaboutno aff
Ivan L. Cameron

Bibliographic record

VenueDefense Technical Information Center (DTIC) · 2007
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCarcinogens and Genotoxicity Assessment
Canadian institutionsnot available
Fundersnot available
KeywordsGenotoxicityMicronucleus testMicronucleusCarcinogenesisJet fuelCarcinogenChemistryBiologyToxicologyMolecular biologyToxicityGeneticsCancer
DOInot available

Abstract

fetched live from OpenAlex

Genotoxicity is often linked to carcinogenesis. The assessment of the genotoxic potential of any "agent" is important in terms of suggesting its carcinogenic potential. Hence, the evaluation of the genotoxic potential of jet fuels, JP-8 and Jet-A has been proposed in these investigations. The rodent micronucleus (MN) assay, which detects micronuclei, arising from both chromosomal fragments and unequal segregation of chromosomes during cell division has been widely applied as an in vivo assay for detecting genotoxic agents. The assay became a standard test system for genotoxicity evaluations in regulatory agencies in several countries (Sofuni 1993, Kirkland 1993, Auletta et al., 1993, Health Protection Branch Genotoxicity Committee, Canada, 1993).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.330
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

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