Seroepidemiology of Human T-Cell Lymphotropic Virus Type-1 (HTLV1) in Mashhad
Bibliographic record
Abstract
INTRODUCTION: Human T-cell lymphotropic virus (HTLV-I) is associated with adult T cell leukemia/lymphoma (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The major routes of HTLV-I transmission are mother-to-child, sexual contact, and blood transfusion. Mashhad is one of the main endemic areas in the world for HTLV-I, and minimizing the risk of HTLV-I transmission through blood transfusion is one of the main duties of the Blood Transfusion Center in Mashhad. The aim of this study was to determine the prevalence of HTLV-I in the blood donor population in Mashhad during 2011-2013. METHODS: All the blood donors in Mashhad from March 2011 to April 2013 who were diagnosed with HTLV-I on the ELISA screening test and the Western blot confirmatory test were included in this seroepidemiological study. RESULTS: From 174,662 blood donors, 327 donors were confirmed to be infected with HTLV-I according to Western blot assay. The seropositive donors ranged in age from 17 to 59, and their mean age was 39.88±10.49 years. The overall prevalence rates of HTLV-I infection were calculated as 0.18% and 0.19%, respectively. CONCLUSION: Due to the lower frequency of infection in regular blood donors, younger individuals, and people with higher education levels, the selection of blood donors from these populations should be further considered.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".