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Record W2162935441 · doi:10.5539/ijb.v6n3p64

Physiological and Ethological Effects of Caffeine, Theophylline, Cocaine and Atropine; Study Using the Ant Myrmica sabuleti (Hymenoptera, Formicidae) as A Biological Model

2014· article· en· W2162935441 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueInternational Journal of Biology · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInsect and Arachnid Ecology and Behavior
Canadian institutionsnot available
FundersKarolinska Institutet
KeywordsHymenopteraCaffeineAtropineAlkaloidConditioningTheophyllineBiologyNeuroscienceToxicologyPharmacologyChemistryZoologyEndocrinologyBotanyMathematics

Abstract

fetched live from OpenAlex

Aiming to check if ants can be used as biological models, we studied the effects of four alkaloids on the ant Myrmica sabuleti. Caffeine and theophylline increased the ants’ linear speed, decreased their precision of reaction and their food consumption, did not affect their response to pheromones, nor their audacity, largely increased their conditioning ability and their memory; ants did not become habituated to nor dependent on these alkaloids. The effects of caffeine exponentially decreased in the course of time; those of theophylline slowly decreased sigmoidally after a latency period. Cocaine decreased the ants’ linear speed, their precision of reaction, their response to pheromones and their consumption of food; it increased their audacity; under its consumption, ants became unable to acquire conditioning. Ants became habituated to and dependent on such an alkaloid. The effects of cocaine rapidly vanished in the course of time. Atropine did not affect the ants’ locomotion, decreased their precision of reaction and their response to pheromones because it reduced their olfactory perception; it did not affect their audacity, decreased their food consumption, increased the speed in acquiring conditioning but not the quality of the resulting conditioning; it slightly increased their memory. Ants did not become habituated to, nor dependent on this alkaloid. The effects of atropine vanished in about 20 hrs - 30 hrs. These effects are in agreement with those known by physiologists, psychologists and doctors in medicine; observations made on ants even lead to more precise deductions. Consequently, ants can efficiently be used as biological models.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.490
Threshold uncertainty score0.318

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.309
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it