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Record W2164504073 · doi:10.1089/neu.2007.0503

Assessment of Posterior Spinal Cord Function with Electrical Perception Threshold in Spinal Cord Injury

2008· article· en· W2164504073 on OpenAlexafffund
John L. K. Kramer, Alastair J. Moss, Philippa Taylor, Armin Curt

Bibliographic record

VenueJournal of Neurotrauma · 2008
Typearticle
Languageen
FieldMedicine
TopicSpinal Cord Injury Research
Canadian institutionsInternational Collaboration On Repair DiscoveriesVancouver Spine Surgery InstituteUniversity of British Columbia
FundersUniversity of British Columbia
KeywordsSpinal cordSpinothalamic tractSensory systemSomatosensory evoked potentialMedicineSpinal cord injurySomatosensory systemNeuroscienceAnatomyCordStimulationLatency (audio)AnesthesiaNociceptionPsychologySurgeryInternal medicine

Abstract

fetched live from OpenAlex

The objective of this study was to evaluate the relevant sensory spinal pathways involved in conveying conduction of electrical perceptual threshold (EPT). In 34 individuals with cervical spinal cord injury (SCI) and eight healthy control subjects, combined EPT and electrical pain perception (EPP), and dermatomal somatosensory evoked potentials (dSSEP) from cervical dermatomes were examined. Stimulation intensities for EPT were recorded to determine quantitative sensory perception and related neurophysiological dSSEP interpretation of posterior spinal cord conduction based on onset latency and waveform configuration. The preservation of EPP in dermatomes was examined relative to EPT to dissociate the involvement of the posterior (dorsal horn and ascending dorsal column) and anterior (decussating and ascending spinothalamic fibers) spinal cord according to different nerve fiber recruitment in the periphery. Pathological EPT values were significantly (p < 0.05) accurate at predicting pathological and abolished dSSEP recordings (>80%), and the mean EPT of pathological and abolished dSSEPs was significantly (p < 0.05) increased compared to non-affected and control dSSEPs. dSSEPs demonstrated normal early onset latency at perceptually low stimulation intensities (<2.5 mA), and selectively absent EPP was dissociated from preserved EPT and/or dSSEP in 22.2% of dermatomes with incomplete sensory deficit. The relationship between EPT and dSSEP interpretation, dSSEP early onset latency and perceptual stimulation intensity, and the dissociation of EPT from EPP suggests that EPT is conducted within the posterior spinal cord. The combination of EPT and EPP with dSSEPs provides reliable quantitative sensory information to assess the segmental integrity of the posterior and anterior spinal cord, and may improve the sensitivity to monitor changes in sensory function after SCI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.519
Threshold uncertainty score0.648

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.126
GPT teacher head0.432
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations44
Published2008
Admission routes2
Has abstractyes

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