Progression of disease in HIV infected children slowed after the first year of life
Bibliographic record
Abstract
(2001) Pediatrics 108, 116. The European Collaborative Study. . Fluctuations in symptoms in human immunodeficiency virus-infected children: the first 10 years of life. . Jul; . : . –22 . [OpenUrl][1][Abstract/FREE Full Text][2] QUESTION: In children with HIV infection at birth, what are the clinical and immunological manifestations of disease progression during the first 10 years of life? Cohort study with a median 5.8 years of follow up. 11 paediatric centres in 7 European countries. 170 HIV infected children who were born to mothers known to be infected with HIV at the time of delivery. Children were categorised into 3 cohorts according to the treatment policy at the time of their birth. Cohort 1 consisted of children born during 1985 to 1988 when no recommendations for treatment existed; cohort 2 consisted of children born during 1989 to 1994 when the treatment policy was restricted to monotherapy for symptomatic children; and cohort 3 consisted of children born during 1995 to 1999 when the initiation of combination treatments was recommended at an early stage. Children were allocated to Centers for Disease … [1]: {openurl}?query=rft.jtitle%253DPediatrics%26rft.stitle%253DPediatrics%26rft.issn%253D0031-4005%26rft.aulast%253DThe%2BEuropean%2BCollaborative%2BStudy%26rft.auinit1%253D%2B%26rft.volume%253D108%26rft.issue%253D1%26rft.spage%253D116%26rft.epage%253D122%26rft.atitle%253DFluctuations%2Bin%2BSymptoms%2Bin%2BHuman%2BImmunodeficiency%2BVirus-Infected%2BChildren%253A%2BThe%2BFirst%2B10%2BYears%2Bof%2BLife%26rft_id%253Dinfo%253Adoi%252F10.1542%252Fpeds.108.1.116%26rft_id%253Dinfo%253Apmid%252F11433063%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=pediatrics&resid=108/1/116&atom=%2Febmed%2F7%2F1%2F27.atom
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How this classification was reachedexpand
Direct model labels (unvalidated)
Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.
| Model arm | Categories | Study design | Confidence |
|---|---|---|---|
| gemma | no category Domain: not available · Genre: Empirical About the Canadian research system: no · About a Canadian topic: no | Observational | low |
| gpt | no category Domain: not available · Genre: Commentary About the Canadian research system: no · About a Canadian topic: no | Observational | medium |
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedLabeled directly by 2 models reading the full record.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".