Occipital nerve stimulation for the treatment of intractable chronic migraine headache: ONSTIM feasibility study
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.
Machine scores (provisional)
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
- Teacher spread
- 0.311 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
BACKGROUND: Medically intractable chronic migraine (CM) is a disabling illness characterized by headache ≥15 days per month. METHODS: A multicenter, randomized, blinded, controlled feasibility study was conducted to obtain preliminary safety and efficacy data on occipital nerve stimulation (ONS) in CM. Eligible subjects received an occipital nerve block, and responders were randomized to adjustable stimulation (AS), preset stimulation (PS) or medical management (MM) groups. RESULTS: Seventy-five of 110 subjects were assigned to a treatment group; complete diary data were available for 66. A responder was defined as a subject who achieved a 50% or greater reduction in number of headache days per month or a three-point or greater reduction in average overall pain intensity compared with baseline. Three-month responder rates were 39% for AS, 6% for PS and 0% for MM. No unanticipated adverse device events occurred. Lead migration occurred in 12 of 51 (24%) subjects. CONCLUSION: The results of this feasibility study offer promise and should prompt further controlled studies of ONS in CM.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Cephalalgia
- Topic
- Migraine and Headache Studies
- Field
- Medicine
- Canadian institutions
- —
- Funders
- National Institute of Neurological Disorders and StrokeAllerganKowa CompanyH. Lundbeck A/SPurdue PharmaSt. Jude MedicalNeuroscience Research AustraliaValeant Pharmaceuticals InternationalGlaxoSmithKlineZogenixBoston Scientific CorporationPfizerPurdue UniversityEli Lilly and Company
- Keywords
- MedicineOccipital nerve stimulationMigraineChronic MigraineMigraine DisordersOccipital neuralgiaStimulationAnesthesiaPhysical medicine and rehabilitationPhysical therapyNeuralgiaAlternative medicineInternal medicineNeuropathic painPathology
- Has abstract in OpenAlex
- yes