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Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial

2012· article· en· 2,960 citations· W2166262263 on OpenAlex· 10.1016/s0140-6736(12)60868-x

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
The Lancet
Topic
Melanoma and MAPK Pathways
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Jewish General Hospital
Funders
GlaxoSmithKline
Keywords
DabrafenibDacarbazineMedicineInternal medicineMelanomaHazard ratioClinical endpointAdverse effectOncologyPhases of clinical researchProgression-free survivalClinical trialRandomized controlled trialGastroenterologySurgeryMetastatic melanomaChemotherapyCancerVemurafenibConfidence intervalCancer research
Has abstract in OpenAlex
no