MétaCan
Menu
Back to cohort
Record W2167633904 · doi:10.1080/13651500600933851

Challenges in the treatment of anxiety disorders: beyond guidelines

2006· article· en· W2167633904 on OpenAlexaff
Raymond W. Lam

Bibliographic record

VenueInternational Journal of Psychiatry in Clinical Practice · 2006
Typearticle
Languageen
FieldPsychology
TopicAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsAnxietyDiscontinuationEscitalopramTolerabilityPsychiatryAdverse effectCognitive behavioral therapyDepression (economics)MedicinePsychologyIntensive care medicineClinical psychologyPsychotherapistInternal medicineAntidepressant

Abstract

fetched live from OpenAlex

Anxiety disorders are highly prevalent, come in many forms and are often chronic, with many patients requiring long-term maintenance therapy. Anxiety and depression may also be comorbid in up to 50% of patients, leading to problems during diagnosis and treatment. Despite their frequency, the recognition and treatment of anxiety disorders is frequently suboptimal, with as few as 15% of patients obtaining treatment consistent with evidence-based care recommendations. Current treatment guidelines for anxiety disorders include a range of pharmacological and non-pharmacological approaches. However, the use of these guidelines alone may not be sufficient to improve patient outcomes. Optimal treatments for anxiety should be based on chronic disease management and balance efficacy with long-term tolerability. Current first-line therapies should include broad-spectrum agents that have proven efficacy in treating both anxiety and depression and are effective across all treatment phases. The allosteric serotonin reuptake inhibitor (ASRI), escitalopram, is a particularly effective treatment, offering high rates of remission combined with relatively low rates of discontinuation due to adverse events. Combination therapy involving medication and psychological approaches, e.g., cognitive behavioral therapy, may also be helpful. Novel approaches to delivering psychotherapy and self-management via the Internet may address accessibility issues for evidence-based psychological treatments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.492
Threshold uncertainty score0.631

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.156
GPT teacher head0.509
Teacher spread0.353 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2006
Admission routes1
Has abstractyes

Explore more

Same venueInternational Journal of Psychiatry in Clinical PracticeSame topicAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesFrench-language works237,207