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The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

2008· review· en· 1,214 citations· W2168448928 on OpenAlex· 10.1038/nrm2346

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.014
GPT teacher head0.317
Teacher spread
0.303 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Reviews Molecular Cell Biology
Topic
Histone Deacetylase Inhibitors Research
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
McGill UniversityMcGill University Health Centre
Funders
National Cancer InstituteNatural Sciences and Engineering Research Council of CanadaAmerican Heart Association
Keywords
BiologyHDAC4ChromatinHistoneGeneticsHistone deacetylaseCell biologyHistone H4Histone deacetylase 5Histone deacetylase 2Multiprotein complexEpigeneticsDNAGene
Has abstract in OpenAlex
no