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Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene

2014· article· en· W2169313581 on OpenAlexaff
Steven Gazal, Karim Sacré, Yannick Allanore, María Teruel, Alison H. Goodall, Shigeto Tohma, Lars Alfredsson, Yukinori Okada, Gang Xie, Arnaud Constantin, Alejandro Balsa, Aya Kawasaki, Pascale Nicaise, Christopher I. Amos, Luis Rodríguez‐Rodríguez, Gilles Chiocchia, Cathérine Boileau, Jinyi Zhang, Olivier Vittecoq, Thomas Barnetche, Miguel Á. González‐Gay, Hiroshi Furukawa, Alain Cantagrel, Xavier Le Loët, Takayuki Sumida, Margarita Hurtado-Nédelec, Christophe Richez, Sylvie Chollet‐Martin, Thierry Schaeverbeke, Bernard Combe, Liliane Khoryati, Baptiste Coustet, Jammel El-Benna, Katherine Siminovitch, Robert M. Plenge, Leonid Padyukov, Javier Martı́n, Naoyuki Tsuchiya, Philippe Dieudé

Bibliographic record

VenueAnnals of the Rheumatic Diseases · 2014
Typearticle
Languageen
FieldMedicine
TopicBone and Dental Protein Studies
Canadian institutionsToronto General HospitalUniversity of Toronto
Fundersnot available
KeywordsMedicineGeneRheumatoid arthritisPhosphoproteinIdentification (biology)ImmunologyGeneticsBiology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.613
Threshold uncertainty score0.528

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.286
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations33
Published2014
Admission routes1
Has abstractno

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