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Record W2170483087 · doi:10.1309/uyn70n9w2dvn9art

Hyperplastic-like Polyps as Precursors of Microsatellite-Unstable Colorectal Cancer

2003· article· en· W2170483087 on OpenAlex
Jeremy R. Jass

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAmerican Journal of Clinical Pathology · 2003
Typearticle
Languageen
FieldMedicine
TopicGenetic factors in colorectal cancer
Canadian institutionsMcGill University
Fundersnot available
KeywordsHyperplastic PolypMicrosatellite instabilityRectumColorectal cancerPathologyMedicineSigmoid colonHyperplasiaCancerInternal medicineGastroenterologyColonoscopyMicrosatelliteBiologyGenetics

Abstract

fetched live from OpenAlex

Journal presents a detailed survey of the morphologic heterogeneity that may be encountered in hyperplastic polyps of the colorectum. Two groups of hyperplastic polyps were compared. The study group comprised 106 colonoscopically obtained hyperplastic polyps from the proximal colon from a series of 91 patients who subsequently had sporadic DNA microsatellite instability–high (MSI-H) cancer in the same anatomic region. The control group comprised 106 hyperplastic polyps from the sigmoid colon or rectum from subjects in whom neoplasia of any type did not develop subsequently. The 2 groups of hyperplastic polyps differed in terms of multiple architectural, cytologic, maturational, and proliferative indices.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.159
Threshold uncertainty score0.759

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.384
Teacher spread0.355 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it