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Record W2170913420 · doi:10.5539/cco.v3n1p25

Extreme Rare Case of Primary Signet Ring Cell Carcinoma of Gall Bladder-Case Report

2014· article· en· W2170913420 on OpenAlexvenueno aff
Ranjit Kumar Padhiari, Niyaz Ahmed, G Praveen, Mira K. Ramesh, Basavaraj Talwar, Vishnu Kurpad

Bibliographic record

VenueCancer and Clinical Oncology · 2014
Typearticle
Languageen
FieldMedicine
TopicCholangiocarcinoma and Gallbladder Cancer Studies
Canadian institutionsnot available
Fundersnot available
KeywordsSignet ring cellSignet ring cell carcinomaMedicineGallbladderCholecystectomyGallstonesMalignancyAdenocarcinomaGastroenterologyCarcinomaPathologyCytokeratinBiopsyInternal medicineCancerImmunohistochemistry

Abstract

fetched live from OpenAlex

Primary carcinoma of the gallbladder is an uncommon malignancy with a variable incidence. Women are affected generally than men (3-4:1) with higher incidence in increasing age. The signet ring cell sub type of adenocarcinoma is a rare and aggressive variant carrying worse prognosis. We report a case of primary signet ring cell carcinoma of gallbladder in a 55yr old woman. Ultrasound showed thickened gallbladder with multiple gallstones. Patient underwent open cholecystectomy. Grossly gallbladder was thickened with multiple stones. Histopathological examination revealed sheets of signet ring cells infiltrating full thickness of the wall. H&E, periodic acid–Schiff (PAS), Alcian blue & Cytokeratin 7 stains confirmed presence of signet ring cells. Post-op Endoscopy with biopsy was done to rule out primary in stomach. Early diagnosis and new lines of treatment in chemotherapy or new biological therapy should be encouraged to improve the survival and life quality.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.200
Threshold uncertainty score0.608

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.091
GPT teacher head0.375
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2014
Admission routes1
Has abstractyes

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