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Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials

2015· article· en· 831 citations· W2171889601 on OpenAlex· 10.1016/s0140-6736(15)60125-8

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.115
GPT teacher head0.357
Teacher spread
0.242 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
The Lancet
Topic
Psoriasis: Treatment and Pathogenesis
Field
Immunology and Microbiology
Canadian institutions
Probity Medical Research
Funders
National Institute for Health and Care ResearchEli Lilly and Company
Keywords
IxekizumabMedicineEtanerceptPlaceboPsoriasisPsoriasis Area and Severity IndexInternal medicineClinical trialBlindingInterleukin 17Physical therapyDermatologyPsoriatic arthritisCytokineTumor necrosis factor alphaSecukinumabPathologyAlternative medicine
Has abstract in OpenAlex
no