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A new class of biophysical models for predicting the probability of decompression sickness in scuba diving

2007· article· en· W2171972779 on OpenAlexaff
Saul Goldman

Bibliographic record

VenueJournal of Applied Physiology · 2007
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and Diving-Related Complications
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsCompartment (ship)WashoutDecompression sicknessInert gasDecompressionKineticsStatistical modelBiological systemChemistryStatisticsMathematicsPhysiologyBiologyMedicineInternal medicineGeologyPhysics

Abstract

fetched live from OpenAlex

Interconnected compartmental models have been used for decades in physiology and medicine to account for the observed multi-exponential washout kinetics of a variety of solutes (including inert gases) both from single tissues and from the body as a whole. They are used here as the basis for a new class of biophysical probabilistic decompression models. These models are characterized by a relatively well-perfused, risk-bearing, central compartment and one or two non-risk-bearing, relatively poorly perfused, peripheral compartment(s). The peripheral compartments affect risk indirectly by diffusive exchange of dissolved inert gas with the central compartment. On the basis of the accuracy of their respective predictions beyond the calibration regime, the three-compartment interconnected models were found to be significantly better than the two-compartment interconnected models. The former, on the basis of a number of criteria, was also better than a two-compartment parallel model used for comparative purposes. In these latter comparisons, the models all had the same number of fitted parameters (four), were based on linear kinetics, had the same risk function, and were calibrated against the same dataset. The interconnected models predict that inert gas washout during decompression is relatively fast, initially, but slows rapidly with time compared with the more uniform washout rate predicted by an independent parallel compartment model. If empirically verified, this may have important implications for diving practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.775
Threshold uncertainty score0.236

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.281
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2007
Admission routes1
Has abstractyes

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