Long-Term Production of Donor-Derived Offspring from Chicken Ovarian Transplants
Bibliographic record
Abstract
A surgical technique for orthotopic transplantation of ovarian tissue was recently developed for chickens, and short-term production of donor-derived offspring from the transplants was demonstrated. The present study evaluated the long-term reproductive function of the transplanted ovaries. In addition, ovarian tissue was transplanted into chicks from eggs that had been treated with busulfan (BU) after 24 h of incubation to reduce the growth of host germ cells. The success rate of ovarian transplantation was not different between BU- and non-BU-treated birds, but the ratio of donor-derived to host-derived offspring was significantly higher in the BU-treated birds. Over the 18-mo period each successfully transplanted hen produced up to 396 eggs with between 50 to 98% of donor-derived progeny. These results demonstrate that when transplanted ovaries attach and develop they can maintain their reproductive function for an extended period of time. These transplantation techniques provide a unique opportunity for development of a practical, efficient protocol for the cryopreservation of germplasm of chickens and may provide an opportunity for regenerating populations of wild birds.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".