Long-Term Production of Donor-Derived Offspring from Chicken Ovarian Transplants
Bibliographic record
Abstract
A surgical technique for orthotopic transplantation of ovarian tissue was recently developed for chickens, and short-term production of donor-derived offspring from the transplants was demonstrated. The present study evaluated the long-term reproductive function of the transplanted ovaries. In addition, ovarian tissue was transplanted into chicks from eggs that had been treated with busulfan (BU) after 24 h of incubation to reduce the growth of host germ cells. The success rate of ovarian transplantation was not different between BU- and non-BU-treated birds, but the ratio of donor-derived to host-derived offspring was significantly higher in the BU-treated birds. Over the 18-mo period each successfully transplanted hen produced up to 396 eggs with between 50 to 98% of donor-derived progeny. These results demonstrate that when transplanted ovaries attach and develop they can maintain their reproductive function for an extended period of time. These transplantation techniques provide a unique opportunity for development of a practical, efficient protocol for the cryopreservation of germplasm of chickens and may provide an opportunity for regenerating populations of wild birds.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".