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ASSESSMENT OF DOMESTIC GOATS AS A PATENT HOST OF ELAPHOSTRONGYLUS CERVI

2002· article· en· W2178707379 on OpenAlexaff
W. Brad Scandrett, Alvin A. Gajadhar

Bibliographic record

VenueJournal of Parasitology · 2002
Typearticle
Languageen
FieldEnvironmental Science
TopicParasite Biology and Host Interactions
Canadian institutionsCanadian Food Inspection Agency
Fundersnot available
KeywordsBiologyLarvaJuvenileFecesVeterinary medicineNematodeEnzooticPhysiologyImmunologyMedicineEcology

Abstract

fetched live from OpenAlex

A study was undertaken to determine whether domestic goats can serve as patent hosts of Elaphostrongylus cervi under natural or experimental conditions. Three-hundred and two fecal samples from 124 domestic goats raised outdoors in New Zealand, where E. cervi is enzootic, were tested for nematode larvae by the Baermann method. All samples were negative for E. cervi dorsal-spined larvae. Twenty juvenile male Nubian and Saanen goats obtained locally were assigned randomly to 5 dosage groups and were orally administered 5, 15, 35, 65, or 125 third-stage larvae of E. cervi, respectively. Two yearling female red deer (Cervus elaphus elaphus) each received 35 or 65 third-stage larvae as positive controls, and 2 uninoculated juvenile male goats served as negative controls. Fecal Baermann testing of pooled samples from the inoculated goats was conducted weekly for the first 80 days postinoculation (DPI) and daily thereafter until 250 DPI. No dorsal-spined larvae were recovered. One goat that had received 15 third-stage larvae displayed a mild transient posterior ataxia suggestive of cerebrospinal elaphostrongylosis. Gross postmortem examination did not reveal any direct evidence of nematodes in any of the goats, and only a few minor lesions were present. Histologically, these lesions were consistent with a parasite etiology. Histological evaluation of grossly normal lumbar and sacral spinal cord from 2 goats that had each received 125 third-stage larvae revealed eosinophilic meningoencephalitis and leukomyelitis, respectively, suggestive of the presence of parasites in the central nervous system. The 2 positive control red deer became patent with dorsal-spined larvae consistent with E. cervi at 131 DPI. These findings suggest that goats, at least those breeds utilized in this study, are not suitable patent hosts for E. cervi.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.053
Threshold uncertainty score0.996

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.375
Teacher spread0.345 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2002
Admission routes1
Has abstractyes

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