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High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

2015· article· en· 1,790 citations· W2180291937 on OpenAlex· 10.1016/j.cell.2015.11.015

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Cell
Topic
CRISPR and Genetic Engineering
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Ontario Institute for Cancer ResearchCanadian Institute for Advanced ResearchHospital for Sick ChildrenLunenfeld-Tanenbaum Research InstituteMount Sinai HospitalUniversity of Toronto
Funders
Canadian Institutes of Health ResearchSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Keywords
BiologyCRISPRGeneComputational biologyGeneticsGenetic FitnessContext (archaeology)Cas9Genome
Has abstract in OpenAlex
no