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Record W2188557045

Mycophenolate mofetil: A potential treatment for reducing proteinuria associated with membranous lupus nephritis.

2003· article· en· W2188557045 on OpenAlexaff
Michela Ferro, Mohammed Yousuf Karim, I C Abbs, David D’Cruz, Munther A. Khamashta, G R Hughes

Bibliographic record

VenueResearch Portal (King's College London) · 2003
Typearticle
Languageen
FieldMedicine
TopicSystemic Lupus Erythematosus Research
Canadian institutionsWomen's Health Research Institute
Fundersnot available
KeywordsMedicineInternal medicineProteinuriaGastroenterologyConcomitantLupus nephritisLupus anticoagulantLupus erythematosusImmunologyAntibodyDiseaseKidneyThrombosis
DOInot available

Abstract

fetched live from OpenAlex

anticoagulant (LA) was present in 69/323 patients (21.4%). aCL were more frequent in patients with seizures than in those without (59.2% vs. 24.7%, RR 3.8 [95%CI 1.8-7.9], p=0.0004). Both IgG and IgM aCL were more frequently found in patients with seizures than in those without (52% vs. 20%, RR 3.6 [95%CI 1.8-7.3], p=0.0006 and 22% vs 7.5%, RR 3.0 [95%CI 1.36.8], p=0.02, respectively). LA was more frequently found in patients with seizures than in those without (25.9% vs 20.6%), but the difference was not statistically significant. Patients were subdivided in those who presented PS and those who presented GS. Patients with PS presented more frequently IgM than those without (25% vs 8%, RR 3.5 [95%CI 1.2-10.1], p=0.04). Patients with GS presented more frequently IgG aCL than those without (60% vs 21.5%, RR 5.1 [95%CI 1.5-17.6], p=0.01). After excluding all patients who had concomitant CVD, the association of PS with IgM aCL and GS with IgG aCL remained significant. Conclusions: aCL are frequently found in SLE patients with seizures, sug

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.223
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.331
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2003
Admission routes1
Has abstractyes

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