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Biomarkers as Inputs

2015· book-chapter· en· W2190389760 on OpenAlexaff
Steven Lehrer

Bibliographic record

VenueOxford University Press eBooks · 2015
Typebook-chapter
Languageen
FieldMedicine
TopicScience, Research, and Medicine
Canadian institutionsQueen's University
Fundersnot available
KeywordsSocioeconomic statusPsychologyBiologyData scienceComputer scienceMedicineEnvironmental healthPopulation

Abstract

fetched live from OpenAlex

Abstract This chapter provides an overview of research primarily within the discipline of economics that empirically examines how biomarkers influences specific health and socioeconomic outcomes. Since the role that biomarkers are hypothesized to play in the estimating equation differs across studies, a distinction is first made between two separate categories of biomarkers: biological time-varying measures such as hormones and biological time-invariant measures including DNA. Recent research in these two categories is then reviewed, focusing on studies that can present the most credible evidence of the role of specific biomarkers. Last, an emerging literature that focuses on the interactions between time-varying environmental conditions and time-invariant genetic factors is discussed. The chapter concludes by highlights three promising areas for future research and suggesting researchers should shift their attention away from investigating specific candidate genes to polygenic risk scores, as well as focus on genetic interactions with more aggregated rather than specific environmental influences.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.775
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.285
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2015
Admission routes1
Has abstractyes

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