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Record W2193305868 · doi:10.1186/s40697-015-0078-1

CanVasc Recommendations for the Management of Antineutrophil Cytoplasm Antibody (ANCA)-Associated Vasculitides – Executive Summary

2015· review· en· W2193305868 on OpenAlexaffabout
Lucy McGeoch, Marinka Twilt, Leilani Famorca, Volodko Bakowsky, Lillian Barra, Susanne M. Benseler, David A. Cabral, Simon Carette, Gerald Cox, Navjot Dhindsa, Christine Dipchand, Aurore Fifi‐Mah, Michèle Goulet, Nader Khalidi, Majed Khraishi, Patrick Liang, Nataliya Milman, Christian A. Pineau, Heather N. Reich, Nooshin Samadi, Kam Shojania, Regina M. Taylor‐Gjevre, Tanveer Towheed, Judith Trudeau, Michael Walsh, Elaine Yacyshyn, Christian Pagnoux

Bibliographic record

VenueCanadian Journal of Kidney Health and Disease · 2015
Typereview
Languageen
FieldMedicine
TopicVasculitis and related conditions
Canadian institutionsUniversité LavalQueen's UniversityResearch CanadaUniversity of SaskatchewanMount Sinai HospitalCanadian Rheumatology AssociationUniversity of TorontoMemorial University of NewfoundlandMcGill UniversityDalhousie UniversityUniversity of OttawaHôpital du Sacré-Cœur de MontréalUniversity of ManitobaNexus Clinical Research (Canada)St. Joseph’s Healthcare HamiltonCentre Hospitalier Universitaire de SherbrookeUniversity of British ColumbiaSt Joseph's Health CareHôtel-Dieu de QuébecHealth Sciences CentreUniversity of CalgaryMcMaster UniversityBC Children's HospitalAlberta Children's HospitalUniversity of AlbertaUniversity Health NetworkOttawa Hospital
FundersF. Hoffmann-La RocheAlexion PharmaceuticalsAmgenPfizerBristol-Myers SquibbGlaxoSmithKline
KeywordsMedicineAnti-neutrophil cytoplasmic antibodyExecutive summaryVasculitisContext (archaeology)RheumatologyANCA-Associated VasculitisInternal medicineNephrologyIntensive care medicineFamily medicineDisease

Abstract

fetched live from OpenAlex

The Canadian Vasculitis research network (CanVasc) is composed of physicians from different medical specialties, including rheumatology and nephrology and researchers with expertise in vasculitis. One of its aims was to develop recommendations for the diagnosis and management of antineutrophil cytoplasm antibody (ANCA)-associated vasculitides in Canada. This executive summary features the 19 recommendations and 17 statements addressing general AAV diagnosis and management, developed by CanVasc group based on a synthesis of existing international guidelines, other published supporting evidence and expert consensus considering the Canadian healthcare context.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.152
Threshold uncertainty score0.303

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.011
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0070.006
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0030.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0140.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.357
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2015
Admission routes2
Has abstractyes

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