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Record W2199002398 · doi:10.1542/peds.2014-3667c

Early Identification of Autism Spectrum Disorder: Recommendations for Practice and Research

2015· article· en· W2199002398 on OpenAlexaff
Lonnie Zwaigenbaum, Margaret L. Bauman, Wendy L. Stone, Nurit Yirmiya, Annette Estes, Robin Hansen, James C. McPartland, Marvin R. Natowicz, Roula Choueiri, Deborah Fein, Connie Kasari, Karen Pierce, Timothy Buie, Alice S. Carter, Patricia A. Davis, Doreen Granpeesheh, Zoe Mailloux, Craig J. Newschaffer, Diana L. Robins, Susanne Smith Roley, Sheldon Wagner, Amy M. Wetherby

Bibliographic record

VenuePEDIATRICS · 2015
Typearticle
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsUniversity of Alberta
FundersAutism Research InstituteMassachusetts General HospitalNational Institute of Mental HealthOrganization for Autism Research
KeywordsMedicineAutism spectrum disorderMultidisciplinary approachIdentification (biology)Psychological interventionAutismClinical PracticeMEDLINEPsychiatryFamily medicine

Abstract

fetched live from OpenAlex

Early identification of autism spectrum disorder (ASD) is essential to ensure that children can access specialized evidence-based interventions that can help to optimize long-term outcomes. Early identification also helps shorten the stressful "diagnostic odyssey" that many families experience before diagnosis. There have been important advances in research into the early development of ASDs, incorporating prospective designs and new technologies aimed at more precisely delineating the early emergence of ASD. Thus, an updated review of the state of the science of early identification of ASD was needed to inform best practice. These issues were the focus of a multidisciplinary panel of clinical practitioners and researchers who completed a literature review and reached consensus on current evidence addressing the question "What are the earliest signs and symptoms of ASD in children aged ≤24 months that can be used for early identification?" Summary statements address current knowledge on early signs of ASD, potential contributions and limitations of prospective research with high-risk infants, and priorities for promoting the incorporation of this knowledge into clinical practice and future research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.109
metaresearch head score (Gemma)0.275
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.109
Threshold uncertainty score0.574

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1090.275
Meta-epidemiology (narrow)0.0040.003
Meta-epidemiology (broad)0.0080.009
Bibliometrics0.0130.011
Science and technology studies0.0040.003
Scholarly communication0.0090.020
Open science0.0130.009
Research integrity0.0200.015
Insufficient payload (model declined to judge)0.0200.009

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.118
GPT teacher head0.413
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations482
Published2015
Admission routes1
Has abstractyes

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Same venuePEDIATRICSSame topicAutism Spectrum Disorder ResearchFrench-language works237,207