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Record W2209143052

Khat (Catha edulis Forsk): A boon or bane to humanity

2010· article· en· W2209143052 on OpenAlexaboutno aff
AW Nyongesa, Daniel W. Onyango

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicForensic Toxicology and Drug Analysis
Canadian institutionsnot available
Fundersnot available
KeywordsKhatCathinoneConsumption (sociology)Traditional medicineMedicineAmphetaminePharmacologySociologySocial science
DOInot available

Abstract

fetched live from OpenAlex

Khat, an evergreen shrub habitually ingested for its euphoric and stimulatory effects, is grown mainly in eastern Africa and south-western Arabia. Its consumption has, for a long time, been restricted to areas close to the sites of production but, because of recent improvement in efficiency and speed of transportation, khat consumption has spread to far flung lands such as North America, Canada, Australia, United Kingdom and parts of Europe. In regions where it is grown, daily life seems to centre on the crop bringing together farmers, traders, middle men, consumers and transporters. Thousands of dollars change hands daily in market centres where khat business is transacted making it the most lucrative business in these regions. The economies of these regions are therefore driven and sustained by khat trade. Khat contains a psychoactive compound belonging to the phenylpropylamine group of alkaloids called cathinone which has amphetamine-like effects. It causes mild euphoria, wakefulness and a host of other effects on regular consumers. Long distance truck drivers are known to constantly chew khat in order to stay awake. Some chewers, however, derive satisfaction in the ability of khat to promote work endurance while others do it for leisure. Consumers generally prefer young leaves and shoots because they contain a more potent active ingredient cathinone which decays within 48 hours to a less potent form called cathine. Despite these positive attributes of khat, it poses serious health risks to consumers arising from the effects of its active ingredient, cathinone, on various organ systems. A number of studies have shown that cathinone has serious effects on cardiovascular, oral and digestive, and urogenital systems. Some of these effects are discussed in details in this chapter.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.057

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0170.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.103
GPT teacher head0.453
Teacher spread0.350 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2010
Admission routes1
Has abstractyes

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