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Prolonged dual antiplatelet therapy in renal failure: a challenging trade-off.

2015· article· en· W2210519680 on OpenAlexaff
Matthias Bossard, Raban Jeger

Bibliographic record

VenuePubMed · 2015
Typearticle
Languageen
FieldMedicine
TopicAntiplatelet Therapy and Cardiovascular Diseases
Canadian institutionsPopulation Health Research InstituteHamilton General Hospital
FundersHarbin Medical UniversityFreiwillige Akademische GesellschaftUniversität Basel
KeywordsMedicineDual (grammatical number)Intensive care medicine

Abstract

fetched live from OpenAlex

Patients with renal failure and coronary artery disease (CAD) represent a complex and delicate cohort. Obviously, their management can be challenging and requires attention and expertise. Globally, the prevalence of chronic kidney disease (CKD), defined as an estimated glomerular filtration rate (eGFR) <60 mL/min per 1.73 m 2 and/or the presence of albuminuria, seems to constantly increase with CKD now having evolved as a global public health issue (1,2). Nowadays, the most important factors promoting the development of CKD worldwide include aging, obesity, diabetes, hypertension and atherosclerotic disease (1-3). Renal failure is not only the consequence of manifold systemic diseases, but also has systemic adverse effects and is related to high morbidity and mortality, even at an early stage (4,5). Among patients with established cardiovascular disease, CKD is related to a higher rate of adverse events, including atherothrombotic manifestations and hemorrhagic events (3). Taken together, those factors contribute to the massive increase in mortality in patients with both CAD and CKD (6).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0000.001
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.236
Teacher spread0.198 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2015
Admission routes1
Has abstractyes

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