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Record W2213143536 · doi:10.1016/j.jpeds.2015.11.033

Efficacy of Low-Dose Buspirone for Restricted and Repetitive Behavior in Young Children with Autism Spectrum Disorder: A Randomized Trial

2015· article· en· W2213143536 on OpenAlexaff
Diane C. Chugani, Harry T. Chugani, Max Wiznitzer, Sumit Parikh, Patricia Evans, Robin Hansen, Ruth Nass, James Janisse, Pamela Dixon-Thomas, Michael E. Behen, Robert Rothermel, Jacqueline S. Parker, Ajay Kumar, Otto Muzik, David J. Edwards, Deborah Hirtz, Huiyuan Jiang, Lalitha Sivaswamy, Ginger Steinhilber, Kristin Kennedy, Kathy Pawlik, R. A. Roeder, Monica Malian, Hailey Turner, Amira Hanna, Jamie Katusin, Deanna Supula, Stacey Halverson, William Guy, Nore Gjolaj, Thomas J. Mangner, Pulak K. Chakraborty, Angela Wigeluk, Gregory Patterson, Melissa Styan Burkett, Anna DeBoard, Jane E. Cornett, M. Lee, Xin Lu, Marianne Majkowski, Beth M. French, Amy Stolinski, Suzi Naguib, Courtney Wolfe-Christensen, Sara Taylor, Jamal Ameli, Julie Kemp McQueeney, Michelle Rubinlicht, Bethany Gorka, Erin Zacharski, Jeffrey L. Blumer, Kathleen Maxwell, Catherine Tasi, Philip Toltzis, Jolee Kalic, Dianne Morus, Jany Paulett, Bonnie Rosolowski, Michael Banchy, Kathryn Westlake, B Calabrò, Carol O. Tacket, Ina Adkins, K H Buchheit, Kathryn Hepper, David Speicher, Susan Bergant, Jennifer Haky, Mary Beth Frohnapfel, Cindy Schaefer, Allison Browning, Roberta Bauer, Rebecca Embacher, Julie Knapp, Stéphanie Lévy, Diane Davies, Donna Lach, John Petrich, Sharon Kreischer, Patty Blubaugh, Mary Ann Morris, Carolyn Garver, Mariam Andersen, Meredith Greene, Amanda Richards, Maria de Fátima Machado Reys Rocha, Ruth Merryman, Sailaja Golla, Julie Long Sherrod, Paulette Perryman, Kara Lorduy, Kathleen Angkustsiri, Lauren B. Plumer, Mary Jacena Leigh, Susan Bacalman, Dorcas L. Roa, Kushma Govindappa, Gayatri Mahajan, Erika Bickel, Norman Brule, Emma Hare, Nadir Sarwary, Dominique Cargill, Joyce Lee, Smiley Hom, Dennis Steindorf, Mandy Pietrykowski, Kindra Root, Sarah M. Coffey, Elise Phelps Hanzel, Adriana Campos Passanezi Sant’Ana, Clara Ramirez, Stefanie Berci, Nielsen Gabriel, Glenn A. Hirsch, Elizabeth Roberts, Amanda Zwilling, Resham Gellatly, Dana Levy, Sandi Lee, Jennifer Rodman, Nora Oberfield, Susan Friedland, Catherine Lord, Rene Kozloff, Celeste Crouse, Stephanie Millen, Alex J. Coímbre, Kelly McCarter, David J. Posey

Bibliographic record

VenueThe Journal of Pediatrics · 2015
Typearticle
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsUniversity of Waterloo
FundersNational Institute of Neurological Disorders and Stroke
KeywordsBuspironeMedicineAutismPlaceboRandomized controlled trialInternal medicinePediatricsPsychiatryAgonist

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.069
Threshold uncertainty score0.474

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.292
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations115
Published2015
Admission routes1
Has abstractno

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