A Natural Fermented Food as a Possible Cause of Syndrome of Inappropriate Secretion of Antidiuretic Hormone
Bibliographic record
Abstract
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is caused by various drugs used in routine medical practice. Manda Koso ® (MK) is a fermented food product that contains many natural materials. Since MK is a natural food, it is considered to have no significant adverse effects. However, here we report a case of SIADH suspected of being induced by MK. A 76-year-old woman presenting with headache and vomiting was admitted. Blood examination revealed severe hyponatremia, with a serum sodium level of 120 mEq/L. Based on the results of careful examination, the diagnosis was SIADH. She had no history of central nervous system disorder or lung disease, and therefore drug-induced SIADH was considered. MK was a suspected product. One month after stopping taking MK, her symptoms disappeared, and serum sodium level, urinary sodium excretion, plasma and urinary osmolality, and plasma ADH level had completely normalized. Clinicians should be noted that a natural fermented food product can induce SIADH. J Endocrinol Metab. 2015;5(6):340-341 doi: http://dx.doi.org/10.14740/jem320w
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".