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Record W2220972584

Short communication: Investigation into sources of contamination of cattle with phenylbutazone

2015· article· en· W2220972584 on OpenAlexaboutno aff
Terence L. Fodey, Wesley G. Smyth, Paul Barnes, Imelda M. Traynor, D. Glenn Kennedy, Steven R. H. Crooks

Bibliographic record

VenueVeterinary Record · 2015
Typearticle
Languageen
FieldEnvironmental Science
TopicPharmaceutical and Antibiotic Environmental Impacts
Canadian institutionsnot available
Fundersnot available
KeywordsPhenylbutazoneMedicineEuropean unionFood safetyDyscrasiaBusinessEnvironmental healthBiotechnologyBiologyPharmacologyPathology
DOInot available

Abstract

fetched live from OpenAlex

PHENYLBUTAZONE (PBZ), also known as ‘bute’, is a NSAID authorised to treat horses suffering from musculoskeletal disorders such as rheumatoid and arthritic diseases and to relieve them from the associated pain. An assessment of PBZ by The Committee for Medicinal Products for Veterinary Use (CVMP) (European Medicines Agency 1997) found that the main health risks to the consumer were blood dyscrasias and the genotoxic/carcinogenic potential for which no thresholds could be identified and so no maximum residue limits could be established. As a consequence of this assessment, PBZ is not permitted for use in any animal destined for the food chain. The risks were reconfirmed more recently in a joint statement by the European Food Safety Authority and European Medicines Agency (2013). In addition to the EU, PBZ is banned from use in food production animals in most other countries, including the USA, Canada and Japan.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.047
Threshold uncertainty score0.254

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.068
GPT teacher head0.295
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

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