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Record W2222432592 · doi:10.2967/jnumed.115.158915

Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report

2015· article· en· W2222432592 on OpenAlexaff
Eben L. Rosenthal, Jason M. Warram, Esther de Boer, James P. Basilion, Merrill A. Biel, Matthew Bogyo, Michael Bouvet, Brian E. Brigman, Yolonda L. Colson, Steven R. DeMeester, Geoffrey C. Gurtner, Takeaki Ishizawa, Paula Jacobs, Stijn Keereweer, Joseph C. Liao, Quyen T. Nguyen, James M. Olson, Keith D. Paulsen, Dwaine Rieves, Baran D. Sumer, Michael F. Tweedle, Alexander L. Vahrmeijer, Jamey P. Weichert, Brian C. Wilson, Michael R. Zenn, Kurt R. Zinn, Gooitzen M. van Dam

Bibliographic record

VenueJournal of Nuclear Medicine · 2015
Typearticle
Languageen
FieldEngineering
TopicNanoplatforms for cancer theranostics
Canadian institutionsPrincess Margaret Cancer CentreUniversity of Toronto
FundersNational Cancer Institute
KeywordsReimbursementMedical physicsMedicineMiamiFood and drug administrationRisk analysis (engineering)Health carePolitical science

Abstract

fetched live from OpenAlex

Navigation with fluorescence guidance has emerged in the last decade as a promising strategy to improve the efficacy of oncologic surgery. To achieve routine clinical use, the onus is on the surgical community to objectively assess the value of this technique. This assessment may facilitate both Food and Drug Administration approval of new optical imaging agents and reimbursement for the imaging procedures. It is critical to characterize fluorescence-guided procedural benefits over existing practices and to elucidate both the costs and the safety risks. This report is the result of a meeting of the International Society of Image Guided Surgery (www.isigs.org) on February 6, 2015, in Miami, Florida, and reflects a consensus of the participants' opinions. Our objective was to critically evaluate the imaging platform technology and optical imaging agents and to make recommendations for successful clinical trial development of this highly promising approach in oncologic surgery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.077
metaresearch head score (Gemma)0.073
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.077
Threshold uncertainty score0.405

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0770.073
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.002
Science and technology studies0.0020.002
Scholarly communication0.0030.004
Open science0.0040.004
Research integrity0.0060.006
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.264
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations147
Published2015
Admission routes1
Has abstractyes

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