Tumour on the tricuspid valve: metastatic osteosarcoma and the heart.
Bibliographic record
Abstract
The antemortem diagnosis of cardiac metastases in osteogenic sarcoma has been documented in only 25 cases over the past 50 years, whereas a prevalence as high as 20% is seen at autopsy, suggesting that cardiac involvement is a late stage complication. As the survival times for primary osteosarcoma continue to improve, previously rare, late stage complications will undoubtedly become more prevalent. In addition to presenting a new case of cardiac metastasis with prolonged survival, the present case report reviews the 25 cases from the literature to illustrate the distinguishing characteristics and clinical presentation, as well as to draw conclusions regarding investigation and management. The demographic differences include female sex, advanced age at the time of diagnosis and longer interval to onset of secondary disease. The clinical characteristics involve hemodynamic compromise or precordial abnormality, with magnetic resonance imaging emerging as the gold standard for diagnosis. Cardiac involvement is a strong predictor of disease elsewhere and mandates careful surveillance, with surgical management likely providing the best outcome.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".