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Curcuma longa on the Metabolic Profile and Atherogenic Index of Rats Fed with a Hyper Caloric Diet

2015· article· en· W2225896400 on OpenAlexvenueno aff
Élen Landgraf Guiguer, Sandra Maria Barbalho, Adriano Cressoni Araújo, Maricelma da Silva Soares de Souza, Patrícia Cincotto dos Santos Bueno, Claudemir Gregório Mendes, Sara da Silva Barbosa, Eliane Paschoal da Silveira, Daniel Pereira Coqueiro

Bibliographic record

VenueJournal of Pharmacy and Nutrition Sciences · 2015
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCurcumin's Biomedical Applications
Canadian institutionsnot available
Fundersnot available
KeywordsCurcumaGlycemicMedicineMetabolic syndromeBody weightTraditional medicineLipid profileType 2 Diabetes MellitusDiabetes mellitusFood sciencePhysiologyInternal medicineEndocrinologyBiology

Abstract

fetched live from OpenAlex

The chronic diseases such as diabetes mellitus, metabolic syndrome and cardiovascular diseases have reached epidemic proportions in developed and developing countries. The high costs of the allopathic medicines represent a growing demand for non-allopathic alternatives. Curcuma longa is usually used as a spice in curries and as a dietary pigment and is considered a medicinal plant due important properties, with anti-inflammatory, anti-oxidant, anti-bacterial and anti-tumor action.The aim of this work was to evaluate the effects of Curcuma longa on the metabolic profile of Wistar rats treated with hyper caloric diet. Forty eight male rats were divided randomly into 4 groups (n=12) and treated for 40 days: G1 that received water (Control Group); G2 that received condensed milk solution ad libitum; G3 that received C. longa by gavage route and G4 that received condensed milk solution ad libitum and C. longa by gavage route. No significant differences for body weight and cholesterol were observed among the groups. Visceral fat, triglycerides and glycaemia were higher in the groups treated with condensed milk but did not differ when comparing G1 with G3 and G2 with G4. Analyzing our results it is possible to say that C. longa may not be efficient to promote benefits in lipid and glycemic profile as well as in the body weight and visceral fat of animals treated with hyper caloric diet.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.177
Threshold uncertainty score0.154

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.327
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

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