MétaCan
← all works

Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial

2016· article· en· 850 citations· W2229483068 on OpenAlex· 10.1016/s0140-6736(15)01120-4

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.075
GPT teacher head0.371
Teacher spread
0.296 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
The Lancet
Topic
Multiple Myeloma Research and Treatments
Field
Medicine
Canadian institutions
Queen Elizabeth II Health Sciences CentreDalhousie UniversityRoyal Victoria HospitalUniversity of British ColumbiaHôpital Maisonneuve-RosemontUniversity of Calgary
Funders
Keywords
DaratumumabMedicineMultiple myelomaRefractory (planetary science)Internal medicineClinical endpointClinical trialPhases of clinical researchSurrogate endpointProteasome inhibitorSurgeryGastroenterologyOncologyLenalidomide
Has abstract in OpenAlex
no