Superhelices with Designed Helical Structures and Temperature-Stimulated Chirality Transitions
Bibliographic record
Abstract
The synthesis of multicomponent superhelices with determined chirality has been realized. By adding water to polymer solution in organic solvents (tetrahydrofuran/ N, N ′-dimethylformamide, THF/DMF), poly(γ-benzyl l -glutamate)- block -poly(ethylene glycol) (PBLG- b -PEG) are able to pack orderly around the surface of PBLG homopolymer bundles with designed helical structures, e.g., right-handed and left-handed, depending on THF/DMF ratio and temperature. A systematic investigation leads to the construction of a temperature–organic solvent composition phase diagram. Before the organic solvents were totally removed, the chirality of the assemblies can be reversibly switched using temperature stimulus. This temperature-stimulated chirality transition of polypeptide superhelices is unprecedented. Circular dichroism (CD) experiments indicated that the packing mode of pending phenyl groups from PBLG chain is responsible for the determination of the helical morphologies.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".