Abstract 3778: Trends in the Incidence, Types and Outcomes of Intracerebral Hemorrhage in Ontario from 1990 - 2010
Bibliographic record
Abstract
Background: Intracerebral hemorrhage (ICH) accounts for approximately 15% of all acute strokes and is associated with the highest stroke mortality. The purpose of this study was to examine the incidence of ICH in Ontario over the last 20 years and investigate whether there have been changes in patient characteristics and treatment interventions over time. Methods: We analyzed data from a provincial administrative database to determine the rates of ICH in Ontario from 1990 to 2010. Data from the Registry of the Canadian Stroke Network (RCSN) from 2003 to 2008 were then used to investigate potential changes in demographic variables (age, gender), stroke severity (Canadian Neurological Scale), comorbidities (hypertension, atrial fibrillation), preadmission medications (warfarin, antihypertensives), hemorrhage location (lobar vs. deep), initial glucose, initial INR and outcomes (modified Rankin Scale at discharge, hospital length of stay) in ICH patients over time. Results: There were 30,353 patients in the administrative database who were admitted with a final diagnosis of ICH between 1990 and 2010. The mean age of these patients was 70.3 years, 51.5% were male and the 30-day mortality rate was 40.6%. The age of patients with ICH increased over this time period (especially in the group >85 years of age), the length of hospital stay shortened and the 30-day mortality rate decreased slightly. Figure 1 shows the sex/age standardized ICH rate per 100,000 by fiscal year, which shows a decline in the ICH rate since 1997. From the 2,466 patients with ICH in the RCSN database from 2003 to 2008, the statistically significant changes included an increase in the lobar hemorrhage rate (39.2% to 46.9%, p=0.0000), an increase in the use of statins at admission (19% to 24%, p=0.0350) and a decrease in the mean systolic blood pressure (173.8±37.5 to 166.4±35.07, p=0.0040). There were no changes over time in neurosurgical interventions (craniotomy or intracranial pressure monitoring). Conclusions: In Ontario, based on hospitalizations, the rate of ICH increased until 1997 and since then has steadily decreased. This decline in the ICH rate over the past 12 years may reflect better management of hypertension.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.002 | 0.004 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".