Contemporary radiation therapy techniques in malignant pleural mesothelioma: a case report
Bibliographic record
Abstract
Malignant pleural mesothelioma (MPM) is a rare but very aggressive neoplasm. Prognosis is poor and the disease is fatalwithin 4-8 months without treatment. Even with a trimodality treatment approach, which has been shown to produce significantmorbidity, median survival does not exceed 11 months. There is a need therefore for exploring new treatment options that canimprove both qualitative and quantitative outcomes. This case report describes locally advanced malignant pleural mesothelioma treated with a unique, customized irradiationtechnique involving a combination of 3D conformal therapy and intensity modulated radiotherapy (IMRT). This allowed fortreatment of the pleura to a high dose, while sparing the lung parenchyma. In this patient, our approach resulted in a prolongedremission. It is our hope that this stimulates new interest in the use of modern day radiation techniques in the treatment of MPM.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".