Abstract 17162: Early and Late Stent Thrombosis are Associated with Long-Term Cardiac Mortality: Results from Pooled PROTECT Trials
Bibliographic record
Abstract
Background: Trials of coronary stents have indicated high mortality risks associated with stent thrombosis (ST), but there have been few adequately powered studies with prospective late follow-up. Methods: The Patient-Related OuTcomes with Endeavor versus Cypher stenting Trial (PROTECT) randomized 8709 subjects to either Endeavor zotarolimus-eluting or Cypher sirolimus-eluting stents, and the PROTECT Continued Access Trial enrolled 1018 patients treated with Endeavor zotarolimus-eluting stents in the U.S. and Canada. Subjects in each were consented for 5 years of follow-up and completed 4 and 3 year follow-up to date respectively. The primary endpoint was ARC definite and probable ST. All potential ST events were stratified by time from index procedure: early (≤30 days), late (>30 and ≤360 days) and very late (>360 days). Baseline characteristics and rates of death and myocardial infarction (MI) were analyzed according to time of ST. Results: The median follow up was 4.1 years. There were 184 ST events: 6...
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.014 | 0.026 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.004 | 0.011 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.003 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.008 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".