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Record W2259045607

Cáncer y apoptosis

2013· article· es· W2259045607 on OpenAlexaff
Cáceres Cortés, Reguera Rosal Julio

Bibliographic record

VenueVertientes. Revista Especializada en Ciencias de la Salud · 2013
Typearticle
Languagees
FieldBiochemistry, Genetics and Molecular Biology
TopicCell death mechanisms and regulation
Canadian institutionsMontreal Clinical Research Institute
Fundersnot available
KeywordsHumanitiesApoptosisBiologyPhilosophyGenetics
DOInot available

Abstract

fetched live from OpenAlex

Muchas enfermedades pueden ser atribuidas a problemas con la apoptosis. Existen enfermedades en lascuales hay una falta de regulacion de la apoptosis la cual contribuye a la patogenesis de dicha enfermedad.La progresion de la enfermedad puede involucrar la acumulacion de celulas, como en el cancer, o la perdidade ellas por un exceso de apoptosis, como en el SIDA La identificacion de los genes y sus productos responsablesde la apoptosis, ha dado lugar al descubrimiento de farmacos algunos de los cuales ya estan en protocolos deinvestigacion clinica. El balance entre las proteinas pro- y antiapoptoticas puede determinar el destino de lascelulas. A este respecto, mucho se ha aprendido acerca de estas dos familias de proteinas y se continuara lainvestigacion para revelar nuevas estrategias para combatir las enfermedades.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.044

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0030.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0130.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.238
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueVertientes. Revista Especializada en Ciencias de la Salud→Same topicCell death mechanisms and regulation→French-language works237,207→