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Record W2260103467 · doi:10.1385/0-89603-336-8:371

High-Performance Electrophoresis Chromatography

2003· article· en· W2260103467 on OpenAlexaff
Serge Desnoyers, Sylvie Bourassa, Guy G. Poirier

Bibliographic record

VenueHumana Press eBooks · 2003
Typearticle
Languageen
FieldEngineering
TopicMicrofluidic and Bio-sensing Technologies
Canadian institutionsUniversité Laval
FundersMedical Research Council
KeywordsChromatographyIon chromatographySize-exclusion chromatographyChemistryAffinity chromatographyImmunoprecipitationAmino acidGel electrophoresisPeptideBiochemistryEnzymeGene

Abstract

fetched live from OpenAlex

Protein purification is important because it gives essential data on an enzyme, like its catalytic activity, its interactions with other proteins or DNA, amino acid quantitation, N-terminal microsequencing, and other information. These analyses will provide important data for designing oligodeoxynucleotide probes for gene cloning and peptide synthesis for antibody production. Purified proteins can be obtained by several methods: gel-filtration chromatography, ion-exchange chromatography, immunoaffinity chromatography, immunoprecipitation, and salt precipitation ( 1 ). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.051
Threshold uncertainty score0.172

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.004
Meta-epidemiology (narrow)0.0060.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0050.003
Science and technology studies0.0020.001
Scholarly communication0.0030.002
Open science0.0060.002
Research integrity0.0020.005
Insufficient payload (model declined to judge)0.0510.080

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.184
Teacher spread0.169 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2003
Admission routes1
Has abstractyes

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